JULÄINE Collagen Biostimulator Treatment

Experience the latest advancement in facial rejuvenation with JULÄINE at Aesthetica Medical. This innovative Swedish collagen biostimulator helps rebuild lost volume, improve skin firmness, and restore facial structure naturally—without the instant, noticeable changes of traditional dermal fillers.
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Restore Your Natural Volume with JULÄINE of Sweden

 As we age, our face changes gradually. Collagen depletion, fat pad descent, and bone remodelling all contribute to hollowing in the temples, flattening of the mid-face, deeper nasolabial folds, and loss of definition around the jawline. JULÄINE works with your body's natural processes to stimulate collagen production, creating subtle, progressive improvements that last 12-24 months.

 What is JULÄINE?

When you choose Aesthetica Medical, you are trusting a clinic committed to excellence, safety, and patient satisfaction.

JULÄINE of Sweden is a next-generation poly-L-lactic acid (PLLA) biostimulator designed to trigger your skin's natural collagen production. Developed by Nordberg Medical after 15 years of biomaterial research, this CE-marked treatment uses advanced LASYNPRO™ microsphere technology to activate collagen regeneration.


Unlike traditional dermal fillers that provide immediate volume, JULÄINE works gradually over approximately three months to rebuild structural support from within. The treatment uses highly uniform PLLA microspheres with smooth surfaces that integrate smoothly into the skin, ensuring even distribution and optimal tissue integration.

Key Benefits of JULÄINE:

• Natural, gradual results that develop over 2-3 months

• Long-lasting effects for 12-24 months after treatment course

• Stimulates your own Type I collagen production

• Safe for delicate areas including temples, under-eyes, and mid-face

• Excellent safety profile with no nodules detected in clinical studies

• Biocompatible and biodegradable - leaves no residue after 24 months

• Subtle volume restoration that doesn't change your appearance dramatically


How Does JULÄINE Work?

JULÄINE uses patented LASYNPRO™ technology to harness the regenerative power of lactic acid. The treatment activates fibroblast cells through mechanical signalling - a natural process that stimulates the skin to renew itself from within.


When injected, the highly uniform PLLA microspheres integrate smoothly into your skin tissue. As they gradually degrade over time, they release L-lactate that stimulates collagen synthesis. This triggers production of healthy Type I collagen, which helps minimise the risk of inflammation, fibrosis, or nodules.


The time-controlled degradation ensures a constant source of product in the tissue, achieving a gradual increase in Type III and Type I collagen for long-lasting, natural results.

JULÄINE vs Traditional Dermal Fillers

Understanding the difference between collagen biostimulators and dermal fillers helps you choose the right treatment for your aesthetic goals.


Dermal Fillers (Hyaluronic Acid):

• Provide immediate volume and results

• Best for instantly replacing significant lost volume

• Results visible straight away

• Typically last 6-18 months depending on product

• Ideal for targeted enhancement and precise contouring


JULÄINE Collagen Biostimulator:

• Works gradually over 2-3 months to build natural collagen

• Best for overall structural restoration and skin tightening

• Creates subtle, progressive improvements

• Results last 12-24 months after treatment course

• Biodegradable - your own collagen provides lasting structure

• Particularly effective for mid-to-lower face volume restoration


Treatment Areas

JULÄINE can be safely administered with a cannula to multiple facial and body areas:


Mid-Face & Cheeks

Restore volume and lift to flattened cheeks, reversing facial fat pad descent and creating more youthful contours. Particularly effective for nasolabial folds and marionette lines.


Temples

Address hollowing in the temple area that contributes to an aged appearance and affects overall facial balance.


Under-Eye Area (Tear Troughs)

Gently improve hollow under-eyes and reduce the appearance of tear troughs. The smooth microspheres make JULÄINE suitable for this delicate area.


Lower Face

Enhance jawline definition and improve the appearance of mild jowling through structural volume restoration and skin tightening.



Body Areas

Neck and décolletage - improving skin quality, firmness, and reducing crepiness

Hands - reducing visibility of veins and tendons while improving overall skin quality

Upper arms, thighs, abdomen - addressing skin laxity and improving texture

Acne scarring and stretch marks - filling and smoothing irregular skin texture



The JULÄINE Treatment Experience

Consultation

Your journey begins with a comprehensive consultation where we assess your facial structure, discuss your concerns, and create a personalised treatment plan tailored to your unique needs.


Treatment Process

The skin is cleansed and disinfected. JULÄINE is administered using a cannula technique, which minimises discomfort and reduces the risk of bruising. The procedure typically takes 10-30 minutes depending on the treatment area.


Comfort

Anaesthesia is generally not necessary, but numbing cream (lidocaine) can be applied beforehand if desired. Most patients experience only mild pressure during injection.


Immediate Aftercare

The injection site may be red and swollen immediately after treatment. This is expected and typically resolves within a few days. 


Downtime

Minimal to none. Most patients return to normal activities immediately. Mild swelling for up to 3 days and possible mild bruising can be easily concealed with makeup. Avoid alcohol for 12 hours and strenuous exercise for 24-48 hours.


Results Timeline & Expectations


Week 1: Initial swelling subsides. Your face returns to baseline. Some patients worry the treatment hasn't worked - this is normal. The regenerative process is just beginning at a cellular level.


Weeks 2-4: You may notice improved skin radiance and texture as fibroblasts begin responding to the PLLA particles and starting collagen production.


Weeks 4-12: This is when visible improvements become apparent. Skin quality improves noticeably, facial contours become more defined, and that healthy, youthful glow returns.


2-6 months: Results continue to improve as collagen regeneration progresses.


Long-term: Results typically last 12-24 months. The PLLA and LASYNPRO™ technology remains in tissues for up to 24 months, after which it's completely biodegradable with no residue.


Treatment Protocol

Most patients achieve optimal results with 2-4 treatment sessions, spaced approximately 4-6 weeks apart. The exact number depends on your age, the condition of the treated area, and your desired outcome. Your practitioner will recommend the ideal protocol during your consultation.


What Results Can You Expect?

JULÄINE delivers incremental, natural-looking improvements:

• Restored elasticity, hydration and improved skin thickness

• Fuller, lifted cheeks with restored mid-face volume

• Reduced appearance of hollow temples for better facial balance

• Less pronounced under-eye hollowing and tear troughs

• Smoothed nasolabial folds and marionette lines

• Improved jawline definition and skin tightening

• Firmer, more radiant skin texture

• Reduced appearance of acne scars and stretch marks


Combining JULÄINE with Other Treatments

At Aesthetica Medical, we often recommend a comprehensive rejuvenation strategy:

• Polynucleotides (e.g., Ameela®) - For skin health, texture improvement, and treating delicate areas like tear troughs. Works well alongside JULÄINE.

• Profhilo - Bio-remodelling for enhanced hydration and firmness

• Dermal Fillers - Can be combined with JULÄINE for targeted volume in specific areas requiring immediate definition

• Radiofrequency Microneedling - Deeper collagen remodelling

• Medical-Grade Skincare - Prescription-strength actives to support collagen production


Ideal Candidates for JULÄINE

JULÄINE is ideal for patients who:

• Are experiencing age-related volume loss and visible skin aging

• Notice hollowing in temples, cheeks, or under-eyes

• Have skin sagging, nasolabial folds, or marionette lines

• Want natural, gradual improvements rather than dramatic instant changes

• Prefer treatments that work with their body's natural processes

• Are looking for long-lasting results (12-24 months)

• Have experienced significant weight loss revealing facial structure

• Have very dry skin, acne scars, or stretch marks


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FREQUENTLY ASKED QUESTION

  • Is JULÄINE painful?

    Most patients report only mild pressure during treatment. The cannula technique minimises discomfort compared to traditional needle injections. Numbing cream can be applied if desired.

  • How long do results last?

    Results typically last 12-24 months after completing a full treatment course. Some patients may see results extending beyond this with maintenance treatments.

  • When will I see results?

    You may notice improved skin radiance within a few weeks. 


    Visible improvements typically appear within 4-6 weeks and continue developing over 2-3 months as collagen production increases.

  • Is there any downtime?

    Downtime is minimal. Some patients experience mild swelling for up to 3 days and possible minor bruising. 


    Most resume normal activities immediately, with any swelling easily concealed by makeup.


  • Can JULÄINE be combined with dermal fillers?

    Yes, many patients benefit from combining both. JULÄINE provides overall structural improvement and collagen stimulation, while fillers address specific areas requiring immediate, targeted volume.


  • Are there any side effects?

    Side effects are minimal and typically include temporary swelling, mild bruising, or tenderness. JULÄINE has an excellent safety profile, with no detection of nodules or granuloma in preclinical and clinical studies.


  • How is JULÄINE different from Sculptra?

    Both are PLLA-based collagen stimulators. JULÄINE is formulated with LASYNPRO™ technology using highly uniform microspheres for smoother integration and more even results. It represents the next generation of PLLA-based biostimulators with advanced purity standards.


  • Is JULÄINE safe?

    Yes, JULÄINE is CE marked and manufactured to ISO 13485:2016 standards in Sweden. PLLA has been used safely in aesthetic medicine for over 25 years. Preclinical data supports the biocompatibility and biodegradability of JULÄINE.


BEFORE & AFTER

Take a look at the results of this treatment.

Why Choose Aesthetica Medical?


Expert Practitioners

Our experienced aesthetic doctors and nurses have extensive training in advanced injection techniques, facial anatomy, and the latest biostimulator technologies.


Personalised Treatment Plans

Every face ages differently. Your treatment plan is tailored to your unique facial structure, concerns, and aesthetic goals through comprehensive consultation and assessment.


Comprehensive Approach

We develop holistic anti-aging strategies combining the most effective modalities - from biostimulators to fillers, toxins, and medical-grade skincare - for optimal results.


Convenient Locations

Clinics in Leeds and Cheshire offer convenient access to advanced aesthetic treatments with the same high standards of care.